1 tablet includes 50 mg ammonium glycyrrhizinate (glycyram).
Additionally: colloidal silicon dioxide, sodium chloride, calcium stearate, microcrystalline cellulose.
1 dose of granules (1.3 grams) includes 25 mg ammonium glycyrrhizinate (glycyram).
Additionally: potato starch, sodium hydrocytrate, milk sugar.
The drug Glyciram is made in the form of tablets of 50 pieces per pack and in the form of metered-dose granules for children (intended for the manufacture of an oral solution), 10 sachets per pack.
Pharmacodynamics and pharmacokinetics
The active ingredient in the drug Glycyram is a mono-ammonium salt glycyrrhizic acidthat is isolated from the thick extract licorice root or obtained from dry raw materials (roots and rhizomes) of plants from the legume family - Glycyrrhiza glabra L. (Licorice naked) and Glycyrrhiza uralensis Fisch. (Ural licorice) Due to the properties of this substance, this drug is characterized anti-inflammatoryefficiency and expectorant moderate action. Also, the remedy has qualities that enable it to stimulate functionality adrenal cortex.
The mechanism of the expectorant action of the drug is associated with the activation of the active ingredient in the ciliary epitheliumlocated in the bronchi and trachea, as well as increased secretory function inherent in the mucous membranes of the upper respiratory tract.
The drug does not significantly affect the activity of the cardiovascular system, however, it slightly increases hypertensive reaction human body on the introduction adrenaline. Also, there is no effect of the drug on m-cholinergic and n-cholinergic systems. Characteristic of glycyramis its anti-inflammatory activity, as well as the ability to reduce vascular permeability. Experimental studies with adrenalectomyproved that the anti-inflammatory effectiveness of the drug is made possible by the participation of the adrenal glands. Ammonium Glycyrrhizinate stimulating functional activity adrenal cortexwhich decreases significantly after hypophysectomy. Also, when taking this therapeutic agent, a slight change in the ratio in serum is noted blood sodium ions/potassium.
Indications for use
The drug Glycyram is indicated for use with:
- pathological conditions of the respiratory tract occurring with hard secret (including similar manifestations in bronchial asthma), as an additional expectorantcomponent of the treatment;
- allergic dermatitis;
- hypotonic syndrome;
- negative manifestations eczema;
- asthenic conditions;
- adrenal insufficiencythat developed against the background of prolonged treatment with glucocorticoids, including the prevention of possible withdrawal syndromeoften observed during a dosage reduction period hormonal drugs or complete cessation of their admission;
- treatment of diencephalic-pituitary forms Addison's disease (both in monotherapy and in parallel with drugs adrenocorticotropic hormone).
It is contraindicated to start taking the remedy Glycyram with:
- personal hypersensitivity patient to the ingredients of tablets or granules;
- heavy pathologies of the heart organic origin;
- serious liver diseases/kidney;
- up to 12 years (for a tablet form of the drug).
With personal sensitivity of the patient to the ingredients of tablets or granules, the occurrence of allergic events.
In the case of prolonged use of this therapeutic agent in high dosages, fluid withdrawal delay out of the body.
Instructions for use Glyciram (method and dosage)
The tablet form of the drug, Glyciram, is recommended for use exclusively for oral (oral) administration by patients who have reached the age of 12 years. Tablets of a medicinal product should be taken in a dose of 50-100 mg (1-2 tablets) twice in 24 hours, 30 minutes after a meal. In more serious cases of the observed disease, an increase in a single dosage of the drug to 100 mg (2 tablets) with a frequency of 3-6 times a day is allowed. The therapeutic course, depending on the diagnosed pathology, can vary from 14 days to 6 months. In each individual case, the dose of the therapeutic agent and the duration of therapy are determined by the attending physician.
For children, this drug is available in a special dosage form, which is dosage granules in 25 mg packets, from which an oral solution is prepared by dissolving the contents of the bag in 20 ml of boiled warm water. I also recommend taking the prepared solution 30 minutes after eating.
For children, the instructions for use of Glyciram recommends the following dosages: from 5 months to 3 years - taking 1 sachet 2 times a day; from 3 years to 5 years - taking 1 sachet 3 times a day; from 5 years to 10 years - taking 1 sachet 3-4 times in 24 hours. The duration of the therapeutic course, depending on the diagnosed pathology, ranges from 3-30 days. In case of emergency, it is possible to increase the number of granules per dilution (on the recommendation of a pediatrician).
With prolonged course admission, you may experience hepatotoxic manifestationsthat require symptomatic treatment.
With the parallel use of glycyram with drugs that stimulate functionality adrenal cortex, amplification of their effects is possible.
Terms of sale
The remedy Glyciram goes on sale.
All therapeutic forms of this drug should be stored at a maximum temperature indicator of a thermometer of 25 ° C in a dry room.
The tablet form of the drug can be stored for 5 years; granules of the drug retain their quality for 2 years.
AnalogsMatches for ATX Level 4 code:EtimizoleKurosurfBroncho MunalAmmonia solutionIRS 19CordiaminePectusin
Glyciram analogs are represented by therapeutic agents of one pharmacological group with similar main efficacy:
- Echinacea (extract, tincture);
For children from 5 months, Glyciram is produced in a special dosage form, which is a dosage granules in 25 mg packets, from which an oral solution is prepared. Children who have reached the age of 12 can be prescribed tablets of this therapeutic agent in a dose of 50 mg.
In pregnancy (and lactation)
The drug Glycyram is contraindicated for taking lactating and pregnant by women.
Reviews for Glyciram
On the Internet, reviews about Glyciram are not common, but those that exist characterize this remedy as quite effective and safe. Of course, abuse this drug due to the effect of its active ingredient on adrenal cortex and arterial pressure should not, the course of therapy should be limited to the framework recommended by the instructions in compliance with the dosages for all age categories.
Price, where to buy
The average price of Glyciram in tablets No. 50 is 260 rubles; in bags No. 10 - 60 rubles.
Also on the Internet you can often find a request for the price of Glyciram spray, which is incorrect, since at this time a medicinal product with this name is available only in the form of tablets and granules.
- Online Pharmacies in Russia
- Glyciram (tablet 50mg No. 50) 239 rub.order