Medication

Remantadine

Structure

Composition of 1 tablet: rimantadine 50 mg Lactose monohydrate, calcium stearate, talc, potato starch as excipients.

Release form

  • Capsules 100 mg.
  • 50 mg tablets

Pharmachologic effect

Antiviral.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Remantadine, what are these pills from? This is an antiviral agent, the main mechanism of which is the inhibition of the early stage of reproduction of the virus after it enters the cell, blocks the transmission of the genetic material of the virus into the cytoplasm of the cell.

Affects the virus flu A and the virus tick-borne encephalitis (arbovirus) Effective when taken in the initial stage of infection (6-7 hours), which reduces the incidence of influenza and the severity of symptoms.

Pharmacokinetics

Slowly but completely absorbed in the digestive tract. 40% bound to blood proteins. The concentration of the active substance in nasal secretion is higher than plasma by 50%. Metabolism occurs in the liver. The elimination half-life is 24-30 hours. It is excreted by the kidneys. In patients with renal failure, it accumulates in toxic concentrations in the absence of dose adjustment.

Indications for use of Remantadine

  • treatment flu in the early stages;
  • epidemic flu prevention;
  • prevention encephalitiscaused by ticks.

Contraindications

  • kidney disease
  • liver disease
  • thyrotoxicosis;
  • age up to 7 years;
  • pregnancy;

With caution is prescribed when arterial hypertension, atherosclerosis, epilepsy. Elderly people with high blood pressure increase their risk hemorrhagic stroke. With a history of epilepsy, the development of an epileptic seizure is possible.

Side effects

  • pain in the stomach anorexiaswelling, dry mouth, nausea;
  • headache, nervousness, insomnia, anxiety, decreased concentration, irritability, drowsiness;
  • allergic reactions.

Instructions for use of Remantadine (Method and dosage)

Remantadine tablets, instructions for use

Tablets are taken orally after meals. For the treatment of influenza take the following scheme: 1st day - 100 mg three times, on the 2nd and 3rd day - 100 mg twice, 100 mg on the 4th day. For the purpose of prevention - 50 mg per day for 10 to 15 days.

How to take the drug with a tick bite? During the first 72 hours, take 100 mg 2 times a day.

Instructions for use Remantadine STI

For the treatment of influenza, it is taken according to the scheme: on the 1st day - 100 mg three times, on the 2nd and 3rd days - 100 mg twice, on the 4th day - 100 mg 1 time. For the purpose of prevention - 50 mg per day for 10 to 15 days. Remantadin Actitab has the same indications and is used in the same dose regimen.

Children from 1 year of age are prescribed Remantadine in syrup. Syrup for children is available under the name Orvire and Algirem. The dosage method will be indicated below.

Overdose

An overdose is manifested by nausea, the appearance of a taste of the metal in the mouth, and the urge to vomit. A psychedelic trip is characteristic, accompanied by fear, panic, delirium, hallucinations, an intense thought process. Intravenous Administration physostigmine 1-2 mg (for adults) and 0.5 mg for children.

Interaction

Adsorbents and enveloping preparations reduce the absorption of the active substance.

Urine acidifying agents decrease the effectiveness of rimantadine, and alkalizing urines increase the effectiveness. Rimantadine clearance decreases when taken cimetidine.

Rimantadine reduces the effect of antiepileptic drugs.

The maximum concentration of the active substance in the blood reduces concomitant use paracetamol and acetylsalicylic acid.

Terms of sale

Without recipe.

Storage conditions

Storage temperature up to 25 ° C.

Shelf life

5 years.

Remantadine for children

Instructions for rimantadine for children: for children 7-10 years old tablets are intended - 50 mg twice, from 10 years - 50 mg three times a day. In severe cases, you can give children 3-7 years old, but at a dose of 1.5 mg / kg / in 2 doses.

Syrup Algirem (rimantadine + matrix carrier alginate) can be used for children from 1 year. Sodium Alginate It has an adsorbing and detoxifying effect, which enhances the antitoxic activity of the drug. To reduce its dosage and reduce the risk of adverse reactions allows a longer circulation time of Algirem in the blood. A teaspoon of syrup contains 10 mg of rimantadine, take it after a meal, according to the scheme.

From 1 to 3 years: 2 tsp. syrup three times a day for 1 day; 2 tsp. twice a day for 2 and 3 days; 4 day - 2 tsp. syrup 1 time.

From 3 to 7 years: 3 tsp. three times a day for 1 day, 3 tsp. twice a day for 2 and 3 days; 4 day - 3 tsp. 1 time.
Effective if taken in the first two days from the onset of the disease. Goes well with Viferon (ointment, gel, rectal suppositories).

Antiviral drugs of other groups: Tamiflu can be prescribed to children older than one year - 2 mg / kg 2 times, and Arbidol approved for use in children from 3 years.

Analogs

Matches for ATX Level 4 code:RimantadineOrvireRemavir

Analogs having one active substance and a similar antiviral effect: Remantadine Stee, Olvirem, Remantidine Actitab, Polirem, Algirem, Arbidol, Kagocel, Tamiflu.

Reviews about Remantadine

Remantadine tablets, what are they taken from? it antiviral drugwhich inhibits the reproduction of the virus. It is a "long-liver" in the market of antiviral drugs - it has been used since 1975. Its prophylactic administration is effective in influenza epidemics in closed groups, as reported in many reviews. However, in recent years, most influenza A viruses (up to 50%) have become resistant to this drug, so it has lost its relevance. It is not effective for other respiratory viral diseases and the A / H1N1 virus, which causes pandemics, is resistant to it. In this connection, the Ministry of Health and Social Development of the Russian Federation does not recommend the use of remantadine in the pandemic period.

Virus susceptibility to class II drugs remains: oseltamivir, zanamivir, peramivir. Class III drugs (aprotinin, camostat) appeared recently and occupy a leading position in the treatment of influenza.

Reviews of Remantadine also contain its use for weight loss. This is based on the fact that one of the side effects of the drug is a decrease in appetite, up to anorexia. It should be noted that the indications for the use of Remantadine do not provide for its administration for this purpose. The presence of side effects, including kidney and liver damage, neuropsychiatric disorders (in 45.5% of cases), anemia does not justify its appointment in order to reduce weight. Agree that a high price you can pay for lost kilograms.

Remantadin price, where to buy

This drug can be easily purchased at any pharmacy. The price of Remantadine depends on the manufacturer, so tablets number 20 from Biochemist (Russia) can be purchased for 57-66 rubles., Remantadin Aktitab Obolenskoe FP ZAO (Russia) is in the same price range. A similar number of tablets Olayfarm (Latvia) costs 189-205 rubles. You do not need a prescription to purchase the drug.

  • Online Pharmacies in Russia
  • Online pharmacies in UkraineUkraine
  • Online pharmacies in Kazakhstan

ZdravCity

  • Remantadine caps. 100mg n10Olinefarm AO171 rub.order
  • Remantadine tablets 50mg No. 20 Biochemist Biochemist OJSC58 rub.order
  • Remantadine tablets 50mg No. 20 OlainfarmOlinefarm AO179 rub.order

Pharmacy Dialog

  • Remantadine tablets 50mg №2065 rub.order
  • Remantadine 50mg tablets №20156 rub.order

Eurofarm * 4% discount on the promotional code medside11

  • Remantadine olaynfarm 50 mg No. 20 tabOlinefarm AO190 rub.order
  • Remantadine 50 mg No. 20 tablets; Tatkhimpharmaceuticals; 85 rubles; order
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Pharmacy24

  • Remantadin-KR 0.05 g No. 20 tablets of PAT "Khimfarmzavod Chervona Zirka", metro Kharkiv, Ukraine 25 UAH order

Pani Pharmacy

  • Remantadine tablets Remantadin-KR tablets 50mg No. 20 Ukraine, Red Star OJSC 30 UAH order
show more

BIOSPHERE

  • Remantadine 100 mg No. 10 caps.Olinefarm (Latvia) 1 tg.order
show more

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