Medication

Dayvonex

Structure

Dayvoneks ointment in 1 milliliter contains 50 micrograms calcipotriol. As auxiliary ingredients, prepared water, trilon B, liquid paraffin, sodium hydrogen phosphate dihydrate, propylene glycol, α-tocopherol, soft white paraffin and macrogol stearate are present.

In 1 milliliter cream 52.2 micrograms present calcipotriolin the form of a monohydrate. Prepared water, sodium hydroxide, white soft paraffin, sodium hydrophosphate dihydrate, trilon B, liquid paraffin, glycerin, cetearyl alcohol, chlorall methylmethamine chloride and macrogol cetostearate are also present.

In 1 milliliter solution 52.2 micrograms present calcipotriolas monohydrate. Auxiliary components: prepared water, levomentholsodium citrate, propylene glycol, isopropanolGOC.

Release form

Available as a topical product in the form of ointment, cream and solution. Ointment and cream are available in aluminum tubes of 30 and 100 grams. The solution is available in a 60 ml plastic bottle.

Pharmachologic effect

The tool is used to treat psoriasis. Active component calcipotriol is an analogue of the active metabolite of the natural vitamin D₃inhibiting the activation of T lymphocytes, which is caused by interleukin 1. The therapeutic effect is to stimulate morphological differentiation and suppress proliferation keratinocytes. Calcipotriol affects calcium metabolism a hundred times weaker than calcitriol.

Dayvoneks - hormonal or not?

Unlike Dayboreta, this drug is not hormonal.

Pharmacodynamics and pharmacokinetics

The active substance is absorbed by 1-5 percent and undergoes rapid biotransformation in the liver, after which pharmacologically inactive metabolites are formed. The half-life is very short.

Indications for use

The drug is prescribed for monotherapy psoriasisas well as with complex treatment psoriasis together with Acitretin, Corticosteroidand Cyclosporine.

The solution is used in areas with the presence of hair.

Contraindications

Ointment and cream can not be used for:

  • children under 18 years old;
  • diseases that are accompanied by a violation of calcium metabolism;
  • hypersensitivity to calcipotrioluor other substance of the drug.

Solution contraindicated in:

  • hypersensitivity to the components of the drug;
  • hypercalciuria;
  • nephrolithiasis;
  • hypervitaminosis D;
  • hypercalcemia.

Caution is necessary when:

  • nephrolithiasis;
  • liver failure;
  • sharp kidney failure;
  • over 65 years old.

Side effects

When using the drug can be observed:

  • swelling of the face;
  • depigmentation reversible nature;
  • periorbital edema;
  • erythema;
  • hyperpigmentation reversible nature;
  • peeling skin;
  • itching;
  • eczema;
  • dry skin;
  • photosensitization;
  • hypercalciuria;
  • exacerbation of the psoriatic process;
  • angioedema;
  • skin burning;
  • different types of rash;
  • skin irritation;
  • contact dermatitis;
  • hypercalcemia;
  • dermatological allergic reactions.

Instructions for use Dayvoneksa (Method and dosage)

According to the instructions for Dayvoneks, ointmentor creamit is necessary to apply a thin layer to the affected areas from one to two times a day. A maximum of 15 grams can be used per day, 100 grams per week. The therapeutic effect is observed after one or two weeks from the start of use. The course of treatment is a maximum of 6-8 weeks.

For solution the maximum dose per week is one vial. It is applied twice a day to the affected areas.

Overdose

The use of high doses can lead to an increase in the concentration of calcium in the blood. In this case, a decrease in muscle tone, thirst, constipation, fatigue and decreased attention span. In this case, you must stop using the drug.

Interaction

Dayvoneks can not be used simultaneously with the funds, which contain salicylic acid and its derivatives.

Terms of sale

It is released without a prescription.

Storage conditions

Store at a temperature not exceeding 25 degrees.

Shelf life

Shelf life of the drug is two years, after opening the tube - six months.

Analogs

Matches for ATX Level 4 code:PsorkutanXamiolBeroxanPsoriaticGive freeAmmifurin

Analogues are Give free, Psorkutan and Glenriasis.

Reviews about Dayvoneks

According to reviews of Dayvoneks at psoriasis, the drug does not help in all cases, therefore it is used only as directed by a doctor.

Also, according to reviews, Give freeand Dayvonexare the main drugs used to treat vulgar psoriasis.

Dayvoneks price, where to buy

The price of Dayvonex ointment in Russia is an average of 1200 rubles per 30 grams.

The price of ointment in Ukraine is an average of 600 hryvnia.

  • Online Pharmacies in Russia

LuxPharma * special offer

  • Dayvoneks ointment tube 30g2290 rub.order

ZdravCity

  • Dayvonex ointment 0.005% 30gLEO Leboratoris Limited1088 rub.order

Pharmacy Dialog

  • Dayvoneks ointment tube 30g1142 rub.order

Eurofarm * 4% discount on the promotional code medside11

  • Dayvonex ointment 30 gLeo Leboratoris Limited1299 rub.order
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